Agilent Multisampler G5668A

For bio-inert modules use bio-inert parts only! For biocompatible modules use bio / biocompatible parts only! Do not mix with bio-inert parts.

When: The needle is visibly damaged. Leaks or blockages are observed. The limit for the needle interaction EMF counter is exceeded. The needle needs to be replaced as part of the yearly maintenance.

Prerequesites: Finish any pending acquisition job. Stop the flow at the pump and remove the solvent lines from the eluent bottles to avoid spilling solvent. Close the shutoff valves at the pump if available.

WARNING: Risk of injury by uncovered needle. An uncovered needle is a risk of harm to the operator. Do not open the safety lock of the needle assembly. Be careful working at the z-robot. Wear safety goggles, when removing the needle assembly.

WARNING: Toxic, flammable and hazardous solvents, samples and reagents. The handling of solvents, samples and reagents can hold health and safety risks. When working with these substances observe appropriate safety procedures (for example by wearing goggles, safety gloves and protective clothing) as described in the material handling and safety data sheet supplied by the vendor, and follow good laboratory practice.

NOTE It is recommended to always exchange the needle assembly and the needle seat at the same time to prevent premature leakage.

In the Agilent Lab Advisor software select Service & Diagnostics > Maintenance Positions > Change Needle, Loop and Seat , click Start and wait until the needle assembly is in maintenance position. OR: In the Local Controller start the maintenance mode and select Change Needle, Loop and Seat function.

Lock the needle in the safety position.

WARNING: When opening capillary or tube fittings solvents may leak out. The handling of toxic and hazardous solvents and reagents can hold health risks.

NOTE: The peristaltic pump cartridge is a replaceable unit. The tubing inside the pump is not replaceable.

Press the two clips on the front of the peristaltic pump cartridge.

Pull the cartridge forward off the motor shaft.

Disconnect the tubing coupler leading to the wash port and the tubing coupler coming from the solvent bottle.

Push the new cartridge onto the motor shaft until the clips click into place.

Connect the wash port tubing to the upper tubing of the new cartridge (use sand paper to get a good grip on the tubing).

Connect the inlet filter of the solvent bottle again. Use the syringe to draw enough solvent for completely filling of the peristaltic pump tubing before continuing to prime the peristaltic pump.

For bio-inert modules use bio-inert parts only! For biocompatible modules use bio / biocompatible parts only! Do not mix with bio-inert parts.

When: Injection volume reproducibility problems are observed. Leaks or blockages are observed. The limit for the rotor seal EMF counter is exceeded. The rotor seal needs to be replaced as part of the yearly maintenance.

CAUTION: Reduced life time of the injection valve. Component cleanliness is crucial for the life time of the injection valve. Replace the rotor seal in a clean environment.

NOTE: Please bear in mind that depending on which valve you have installed the images may slightly differ from the actual item.

Remove all capillaries from the injection valve with a 1/4 inch wrench.

NOTE: Remember the correct plumbing. Check the drawing on the side cover of the hydraulic box for correct plumbing.

Use a 9/64 inch hex driver to unscrew the two socket screws which hold the stator head in place.

CAUTION: Damage to the stator head. The polished sealing surface of the stator head contains six ports that access handling can easily damage. Avoid touching the polished surface of the stator head. Never place the polished surface on a hard surface.

Before you start the new drawer installation you have to remove the lower drawer (2H drawer = default configuration) from the Sample Hotel.

For best cooling performance the 2H drawer must be installed in the lowest position.

More detailed video information is available on the Agilent Information Center.

Pull the drawer completely out.

Unlatch the drawer: Use a screwdriver to press the clamping lever lightly to the left.

Remove the drawer from the rail guide.

The drawer is now out of the hotel.

Grab in the recession below the dummy drawer front panel and lift the left side.

Warning: For bio-inert modules use bio-inert parts only!

Prerequisites: Cleaning tissue, Appropriate solvent like isopropanol or methanol

Start the maintenance mode and select Service Position in the Local Controller OR in the Agilent Lab Advisor software select Service & Diagnostics in the system screen (Tools) > Maintenance Positions > Change Metering Device , click start and wait until the metering device is in maintenance position.

Capillaries and valves removed from the flush head

Flush Head detached from the actuator

Flush head separated from the hydraulic box

Flush head, head body and the piston separated